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Rebecca Dickstein, Ph.D. has long standing research interests in symbiotic nitrogen
fixation (SNF) in legumes with extensive experience in the model legume Medicago truncatula.
Dr. Dickstein uses genetic approaches to study how the rhizobial symbiont infects
host plant roots and what processes are essential in the latter stages of SNF. This
work recently led the identification of several, as-yet unpublished, crucial putative
transporters. It also led to the serendipitous discovery that expressing a specific
transporter in plants leads to plants with enhanced growth. Dr. Dickstein has expertise
in genetics, molecular biology, biochemistry and biotechnology. In addition to research,
Dr. Dickstein teaches the large, cross-listed undergraduate and graduate course Biochemistry
I: Macromolecular Structure and Function each fall. During spring semesters, Dr. Dickstein
teaches a graduate course alternating between Advanced Molecular Biology, Signal Transduction
and Biochemical Regulation and a Topics course in SNF. Dr. Dickstein was promoted
to Professor in 2007, having started at the University of North Texas in 2000 as an
Associate Professor with tenure. She was at Drexel University as Assistant Professor,
then Associate Professor from 1990-2000. She holds a BS in Biochemistry from Pennsylvania
State University and a PhD in Biochemistry from Johns Hopkins University. Her long-standing
interest in SNF in legumes dates from when she was a PhD student investigating the
expression of bacterial genes in eukaryotic organisms. She has actively participated
in SNF research since her Post-doc work at Massachusetts General Hospital and Harvard
University from 1985 to 1989.
CURRENT RESEARCH INTERESTS
- Symbiotic nitrogen fixation.
- Biological transporters.
- Nitrogen use and assimilation.
- Rhizobial infection of legume roots.
FOR PROSPECTIVE GRADUATE STUDENTS
Not accepting new students at this time
CURRENT GRANT-FUNDED PROJECTS
- National Science Foundation Genome Enabled Plant Research. IOS-1127155. GEPR: Genetic
and cellular dissection of mutualistic plant-microbe symbioses in Medicago truncatula.
(Co-PI). $770,696. 3/15/12-2/26/17.
RECENT SIGNIFICANT PUBLICATIONS
- Veerappan, V., Jani, M., Kadel, K., Troiani, T., Gale, R., Mayes, T., Shulaev, E.,
Wen, J., Mysore, K., Azad, R.K. and Dickstein, R. (2016). Rapid identification of
causative insertions underlying Medicago truncatula Tnt1 mutants defective in symbiotic
nitrogen fixation from a forward genetic screen by whole genome sequencing. BMC Genomics
17:141. doi: 10.1186/s12864-016-2452-5.
- Veerappan, V., Kadel, K., Alexis, N., Scott, A., Kryvoruchk, I., Sinharoy, S., Taylor,
M., Udvardi, M. and Dickstein. R. (2014). Keel petal incision: A simple and efficient
technique for genetic crossing in Medicago truncatula. Plant Methods 10:11.
- Salehin, M., Huang, Y.-S., Bagchi, R., Sherrier, D.J. and Dickstein, R. (2013). Allelic
differences in Medicago truncatula NIP/LATD mutants correlate with their encoded proteins'
transport activities in planta. Plant Signal. & Behavior 8:1-5.
- Bagchi, R., Salehin, M., Adeyemo, O.S., Salazar, C., Shulaev, V., Sherrier, D.J. and
Dickstein, R. (2012). Functional assessment of the Medicago NIP/LATD protein demonstrates
that it is a high affinity nitrate transporter. Plant Physiology 160: 906-916.
- Meckfessel, M.H., Blancaflor, E.B., Plunkett, M., Dong, Q. and Dickstein, R. (2012).
Multiple domains in MtENOD8 protein including the signal peptide target it to the
symbiosome. Plant Physiology 159: 299-310.
- Léran, S., Varala, K., Boyer, J.C., Chiurazzi, M., Crawford, N., Daniel-Vedele, F.,
David, L., Dickstein, R., Fernandez, E., Forde, B., Gassman, W., Geiger, D., Gojon,
A., Gong, J.M., Halkier, B.A., Harris, J.M., Hedrich, R., Limami, A.M., Rentsch, D.,
Seo, M., Tsay, Y.F., Zhang, M., Coruzzi, G. and Lacombe, B. (2014). A unified nomenclature
of NITRATE TRANSPORTER 1/PEPTIDE TRANSPORTER family members in plants. Trends Plant
Science 19:5-9. doi: 10.1016/j.tplants.2013.08.008.
- Salehin, M., Bagchi, R., Huang, Y.-S., Adeyemo, O.S., Sherrier, D.J. and Dickstein,
R. (2015). The Medicago truncatula NIP/LATD transporter is essential for nodulation
and appropriate root architecture. In, Biological Nitrogen Fixation, Volume I, Biological
Nitrogen Fixation. Frans J. de Bruijn (Editor). ISBN: 978-1-118-63712-8. Wiley-Blackwell.
- Libault, M. and Dickstein, R. (2014). Advances in functional genomics research in
legumes. In Legumes in the 'Omic Era, Springer New York (Gupta, S., Nadarajan, N.,
Gupta, D.S. eds.). http://link.springer.com/chapter/10.1007/978-1-4614-8370-0_2.
PATENTS
- MtNIP regulated plants with significantly increased size and biomass. R. Dickstein,
M. Salehin and R. Bagchi. US patent number US 9,297,021. Issued March 29, 2016.