
Research Scientist 1
Office:
Room #B328
Department of Biological Sciences, College of Arts and Sciences, University of North Texas, Denton, TX 76203
940-565-4532
Gail.Shadle@unt.edu
Education:
B.S. | Biology/Chemistry, Lock Haven University of Pennsylvania, Lock Haven, PA - 1999 |
Research:
Feb/2013 - present | Research Scientist 1, (Supervisor: Dr. Richard A. Dixon) Department of Biological Sciences, University of North Texas. |
Jan/2006 - Jan/2013 | Research Associate, (Supervisor: Dr. Richard A. Dixon) the Samuel Roberts Noble Foundation, Plant Biology Division. |
June/1999 - Dec/2005 | Research Assistant. (Supervisor: Dr. Richard A. Dixon) the Samuel Roberts Noble Foundation, Plant Biology Division. |
Jan/1999 - May 1999 | Laboratory Assistant. Lock Haven University of Pennsylvania, Biochemistry laboratory. |
Aug/1998 - Dec/1998 | Laboratory Assistant. (Supervisor: Dr. Ted Nuttall) Lock Haven University of Pennsylvania, Cellular and Molecular Biology laboratory. |
Publications:
- Zhao, J., Huhman, D.V., Shadle, G., He, X-Z., Sumner, L.W., Tang, Y. and Dixon, R. A. (2011). MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula. Plant Cell, 23, 1536-1555.
- Zhou, R., Jackson, L., Shadle, G., Nakashima, J., Temple, S., Chen, F. and Dixon, R.A. (2010). Distinct cinnamoyl CoA reductases involved in parallel routes to lignin in Medicago truncatula. Proceedings of the National Academy of Sciences USA 107 (41), 17803-17808.
- Jackson, L., Shadle, G., Zhou, R., Nakashima, J., Chen, F. and Dixon, R.A. (2008). Improving saccharification efficiency of alfalfa stems through modification of the terminal stages of monolignol biosynthesis. BioEnergy Research 1, 180-192.
- Nakashima, J., Chen, F., Jackson, L., Shadle, G. and Dixon, R.A. (2008). Multi-site genetic modification of monolignol biosynthesis in alfalfa (Medicago sativa L.) : effects on lignin composition in specific cell types. New Phytologist 179, 738-750.
- Shadle, G., Chen, F., Reddy, M.S.S., Jackson, L., Nakashima, J. and Dixon, R.A. (2007). Down-regulation of hydroxycinnamoyl CoA:shikimate hydroxycinnamoyl transferase in transgenic alfalfa affects lignification, development and forage quality. Phytochemistry 68, 1521-1529.
- Chen, F., Reddy, M.S.S., Temple, S., Jackson, L., Shadle, G. and Dixon, R.A. (2006) Multi-site genetic modulation of monolignol biosynthesis suggests new routes for the formation of syringyl lignin and wall-bound ferulic acid in alfalfa (Medicago sativa L.). Plant Journal 48, 113-124.
- Reddy, M.S.S., Chen, F., Shadle, G., Jackson, L., Aljoe, H. and Dixon, R.A. (2005). Targeted down-regulation of cytochrome P450 enzymes for forage quality improvement in alfalfa (Medicago sativa L.). Proceedings of the National Academy of Sciences USA 102, 16573-16578.
- Suzuki, H., Xia, Y., Cameron, R., Shadle, G., Blount, J., Lamb, C. and Dixon, R.A. (2004). Signals for local and systemic responses of plants to pathogen attack. Journal of Experimental Botany 55, 169-179.
- Shadle, G., Wesley, S.V., Korth, K. L., Chen, F., Lamb, C. and Dixon, R.A. (2003). Phenylpropanoid compounds and disease resistance in transgenic tobacco with altered expression of L-phenylalanine ammonia-lyase. Phytochemistry 64, 153-161.
- Jackson, L., Chen, F., Nakashima, J., Shadle, G., and Dixon, R.A. "Cinnamoyl CoA reductase down-regulation and its impact on forage quality in alfalfa (Medicago sativa)." American Society of Plant Biologists, July 7-11, 2007, Chicago, IL.
- Shadle, G., Chen, F., Jackson, L., and Dixon, R.A. "Down-regulation of cinnamyl alcohol dehydrogenase and its impact on forage quality in alfalfa (Medicago sativa)." American Society of Plant Biologists, July 7-11, 2007, Chicago, IL.
- Jackson, L., Chen, F., Nakashima, J., Shadle, G., Reddy, M.S.S. and Dixon, R.A. "Studying monolignol biosynthesis in alfalfa by the down-regulation of Cinnamoyl CoA reductase." Phytochemical Society of North America Annual Meeting, July 8-12, 2006, Oxford, MS.
- Shadle, G., Chen, F., Nakashima, J., Jackson, L., Reddy, M.S.S. and Dixon, R.A. "Effects of down-regulation of HCT on lignin in alfalfa." Phytochemical Society of North America Annual Meeting, July 8-12, 2006, Oxford, MS.
- Nakashima, J., Reddy, M.S.S., Chen, F., Shadle, G., Jackson, L., and Dixon, R.A. "Down-regulation of key enzymes in the monolignol pathway: effects on lignin composition in specific cell types of alfalfa (Medicago sativa L.)" Phytochemical Society of North America Annual Meeting, July 8-12, 2006, Oxford, MS.
- Jackson, L., Reddy, M.S.S., Shadle, G., Chen, F., and Dixon, R.A. "p-Coumarate 3 -hydroxylase down-regulation in alfalfa and its impact on monolignol biosynthesis." American Society of Plant Biologists, July 16-20, 2005, Seattle, WA.
- Reddy, M.S.S, Chen, F.,, Shadle, G., Jackson, L., and Dixon, R.A. "Understanding monolignol biosynthesis in Medicago sativa by a reverse genetics approach." American Society of Plant Biologists, July 24-28, 2004, Orlando, FL.
- Shadle, G., Jackson, L., Reddy, M.S.S, Chen, F.,, and Dixon, R.A "Modification of Lignin in Medicago by Down-Regulation of Ferulate 5-Hydroxylase." Society for In Vitro Biology Annual Meeting, May 22-26, 2004, San Francisco, CA.
- Jackson, L., Shadle, G., Reddy, M.S.S, Chen, F.,, and Dixon, R.A. "Understanding monolignol biosynthesis in Medicago by downregulation of p-coumarate 3-hydroxylase." Society for In Vitro Biology Annual Meeting, May 22-26, 2004, San Francisco, CA.
- He, X.Z., Suzuki, H., Achnine, L., Shadle, G., Jackson, L., Clouse, J. and Dixon, R.A. "Characterization of squalene epoxidase promoter in tobacco cell suspension cultures." XVth International Plant Protection Congress, May 11-16, 2004, Beijing, China.
- Jackson, L., Shadle, G., Reddy, M.S.S, Chen, F.,, and Dixon, R.A. "A reverse genetics approach to lignin modification in Medicago." Phytochemical Society of North America Annual Meeting, August 9-13, 2003, Peoria, IL.
- He, X.Z., Suzuki, H., Achnine, L., Shadle, G., Clouse, J., and Dixon, R.A. "Differential regulation of squalene epoxidase in response to methyl jasmonate induction in tobacco and alfalfa cell suspension cultures." Gordon Conference in Agricultural Science, April 2003, Ventura, CA.
- Shadle, G., Reddy, M.S.S, Jackson, L., Chen, F.,, and Dixon, R.A. "A reverse genetics approach to study the biosynthesis of monolignols in Medicago." Second Oklahoma Minisymposium in Molecular Plant Biology, March 20-21, 2003, Stillwater, OK.
- Deavours, B.E., Steele, C., Shadle, G., and Dixon, R.A. "Metabolic engineering of isoflavonoid biosynthesis in alfalfa." Second Oklahoma Minisymposium in Molecular Plant Biology, March 20-21, 2003, Stillwater, OK.
- Shadle, G., Wesley, S.V., Korth, K. L., Chen, F., Lamb, C., and Dixon, R.A. "Over-expression of L-phenylalanine ammonia-lyase improves plant resistance to viral, fungal, and bacterial pathogens." XXI International Conference on Polyphenols, September 9-12, 2002, Marrakech, Morocco.
- Boydston, C., Riner, L., Shadle, G., Allen, S., Dixon, R.A, May, G., Paiva, N.L., and Harrison, M.J. "Insertional mutagenesis of Medicago truncatula." 4th Workshop on Medicago truncatula, July 7-10, 2001, Madison, WI.